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An optical density detection platfor...

Mosteller, Matthew Philip.

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An optical density detection platform with integrated microfluidics for in situ growth, monitoring, and treatment of bacterial biofilms.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	An optical density detection platform with integrated microfluidics for in situ growth, monitoring, and treatment of bacterial biofilms./
作者:	Mosteller, Matthew Philip.
面頁冊數:	184 p.
附註:	Source: Masters Abstracts International, Volume: 51-05.
Contained By:	Masters Abstracts International51-05(E).
標題:	Engineering, Biomedical. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1535570
ISBN:	9781303016097

An optical density detection platform with integrated microfluidics for in situ growth, monitoring, and treatment of bacterial biofilms.
Mosteller, Matthew Philip.

An optical density detection platform with integrated microfluidics for in situ growth, monitoring, and treatment of bacterial biofilms. - 184 p.

Source: Masters Abstracts International, Volume: 51-05.

Thesis (M.S.)--University of Maryland, College Park, 2012.

Systems engineering strategies utilizing platform-based design methodologies are implemented to achieve the integration of biological and physical system components in a biomedical system. An application of this platform explored, in which an integrated microsystem is developed capable of the on-chip growth, monitoring, and treatment of bacterial biofilms for drug development and fundamental study applications. In this work, the developed systems engineering paradigm is utilized to develop a device system implementing linear array charge-coupled devices to enable real time, non-invasive, label-free monitoring of bacterial biofilms. A novel biofilm treatment method is demonstrated within the developed microsystem showing drastic increases in treatment efficacy by decreasing both bacterial biomass and cell viability within treated biofilms. Demonstration of this treatment at the microscale enables future applications of this method for the in vivo treatment of biofilm-associated infections.

ISBN: 9781303016097Subjects--Topical Terms:

1017684
Engineering, Biomedical.

An optical density detection platform with integrated microfluidics for in situ growth, monitoring, and treatment of bacterial biofilms.
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