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Postmortem distribution of zolpidem ...

Thompson, Kristi S.

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Postmortem distribution of zolpidem in aviation accident victims.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Postmortem distribution of zolpidem in aviation accident victims./
作者:	Thompson, Kristi S.
面頁冊數:	91 p.
附註:	Source: Masters Abstracts International, Volume: 51-06.
Contained By:	Masters Abstracts International51-06(E).
標題:	Health Sciences, Toxicology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1538065
ISBN:	9781303106477

Postmortem distribution of zolpidem in aviation accident victims.
Thompson, Kristi S.

Postmortem distribution of zolpidem in aviation accident victims. - 91 p.

Source: Masters Abstracts International, Volume: 51-06.

Thesis (M.S.)--University of Central Oklahoma, 2013.

The purpose of the study was to confirm there is a consistent postmortem distribution of zolpidem in postmortem blood and body tissues, and/or fluids making it possible to estimate zolpidem blood concentrations from fluid and tissue concentrations. The samples for the study were zolpidem-positive fatalities located in the CAMI ToxFlo database at the FAA's Bioaeronautical Sciences Research Laboratory. A UPLC/MS method was developed and validated. The LDR, LOD, LOQ, accuracy, precision, and matrix effect were evaluated. The specimens were analyzed for the distribution of zolpidem. The results of this study confirmed there is a consistent postmortem distribution of zolpidem found in the spleen, kidney, and lung; making it possible to roughly estimate, zolpidem blood concentrations from these tissues.

ISBN: 9781303106477Subjects--Topical Terms:

1017752
Health Sciences, Toxicology.

Postmortem distribution of zolpidem in aviation accident victims.
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245 1 0 $a Postmortem distribution of zolpidem in aviation accident victims.
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500 $a Source: Masters Abstracts International, Volume: 51-06.
500 $a Adviser: David L. von Minden.
502 $a Thesis (M.S.)--University of Central Oklahoma, 2013.
520 $a The purpose of the study was to confirm there is a consistent postmortem distribution of zolpidem in postmortem blood and body tissues, and/or fluids making it possible to estimate zolpidem blood concentrations from fluid and tissue concentrations. The samples for the study were zolpidem-positive fatalities located in the CAMI ToxFlo database at the FAA's Bioaeronautical Sciences Research Laboratory. A UPLC/MS method was developed and validated. The LDR, LOD, LOQ, accuracy, precision, and matrix effect were evaluated. The specimens were analyzed for the distribution of zolpidem. The results of this study confirmed there is a consistent postmortem distribution of zolpidem found in the spleen, kidney, and lung; making it possible to roughly estimate, zolpidem blood concentrations from these tissues.
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650 4 $a Chemistry, Analytical. $3 586156
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