東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

The ecology of colicins.

Kirkup, Benjamin C., Jr.

Linked to FindBook

Google Book

Amazon

博客來

The ecology of colicins.

Record Type:	Electronic resources : Monograph/item
Title/Author:	The ecology of colicins./
Author:	Kirkup, Benjamin C., Jr.
Description:	200 p.
Notes:	Source: Dissertation Abstracts International, Volume: 65-03, Section: B, page: 1123.
Contained By:	Dissertation Abstracts International65-03B.
Subject:	Biology, Ecology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3125228
ISBN:	0496725181

The ecology of colicins.
Kirkup, Benjamin C., Jr.

The ecology of colicins. - 200 p.

Source: Dissertation Abstracts International, Volume: 65-03, Section: B, page: 1123.

Thesis (Ph.D.)--Yale University, 2004.

Colicins, specific and highly potent toxins, have been presumed to serve the Escherichia coli that produce them in mediating population-level and/or community level interactions in the wild. Prior attempts to assess the role of colicins have found them to play a significant role in invasion or defense of laboratory environments, but have failed to show a reproducible effect under more natural settings. The goal of this research is to incorporate mathematical and experimental methods to permit studies of the ecology of colicins in vivo. These methods include the use of strains of E. coli that are isogenic save for the production of, resistance or sensitivity to one of two colicins. These strains were studied with both in vitro and in vivo methods. Most compelling, experiments in mice reveal that colicins are effective antagonistic agents and that a trio of strains, including a sensitive, a producer, and a resistant strain, forms a non-transitive system recognizable as the rock-paper-scissors model from game theory. In theory, the non-transitive structure of this trio leads to cycling among the strains. This cycle was observed in vivo .

ISBN: 0496725181Subjects--Topical Terms:

1017726
Biology, Ecology.

The ecology of colicins.
LDR:02005nmm 2200289 4500 001 1852023
005 20051229075124.5
008 130614s2004 eng d
020 $a 0496725181
035 $a (UnM)AAI3125228
035 $a AAI3125228
040 $a UnM $c UnM
100 1 $a Kirkup, Benjamin C., Jr. $3 1939899
245 1 4 $a The ecology of colicins.
300 $a 200 p.
500 $a Source: Dissertation Abstracts International, Volume: 65-03, Section: B, page: 1123.
500 $a Director: Margaret A. Riley.
502 $a Thesis (Ph.D.)--Yale University, 2004.
520 $a Colicins, specific and highly potent toxins, have been presumed to serve the Escherichia coli that produce them in mediating population-level and/or community level interactions in the wild. Prior attempts to assess the role of colicins have found them to play a significant role in invasion or defense of laboratory environments, but have failed to show a reproducible effect under more natural settings. The goal of this research is to incorporate mathematical and experimental methods to permit studies of the ecology of colicins in vivo. These methods include the use of strains of E. coli that are isogenic save for the production of, resistance or sensitivity to one of two colicins. These strains were studied with both in vitro and in vivo methods. Most compelling, experiments in mice reveal that colicins are effective antagonistic agents and that a trio of strains, including a sensitive, a producer, and a resistant strain, forms a non-transitive system recognizable as the rock-paper-scissors model from game theory. In theory, the non-transitive structure of this trio leads to cycling among the strains. This cycle was observed in vivo .
590 $a School code: 0265.
650 4 $a Biology, Ecology. $3 1017726
650 4 $a Biology, Microbiology. $3 1017734
650 4 $a Health Sciences, Public Health. $3 1017659
690 $a 0329
690 $a 0410
690 $a 0573
710 2 0 $a Yale University. $3 515640
773 0 $t Dissertation Abstracts International $g 65-03B.
790 1 0 $a Riley, Margaret A., $e advisor
790 $a 0265
791 $a Ph.D.
792 $a 2004
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3125228