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Isolating bold fMRI correlates of in...

Hamilton, Andrew A. J.

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Isolating bold fMRI correlates of interhemispheric visual processing: A comparison of parametric and exploratory analysis techniques.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Isolating bold fMRI correlates of interhemispheric visual processing: A comparison of parametric and exploratory analysis techniques./
Author:	Hamilton, Andrew A. J.
Description:	73 p.
Notes:	Source: Masters Abstracts International, Volume: 43-02, page: 0501.
Contained By:	Masters Abstracts International43-02.
Subject:	Biophysics, Medical. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MQ94116
ISBN:	0612941167

Isolating bold fMRI correlates of interhemispheric visual processing: A comparison of parametric and exploratory analysis techniques.
Hamilton, Andrew A. J.

Isolating bold fMRI correlates of interhemispheric visual processing: A comparison of parametric and exploratory analysis techniques. - 73 p.

Source: Masters Abstracts International, Volume: 43-02, page: 0501.

Thesis (M.Sc.)--Dalhousie University (Canada), 2004.

Blood-oxygen level-dependent (BOLD) functional MRI is currently used to measure the haemodynamic response in gray matter regions of the brain, but activity in these regions is thought to represent only the input signal to a neuron. It is also important to measure the output and the connectivity of neural activation (in white matter), but the BOLD contrast in this respect suffers from very low SNR and activation has proven difficult to detect. This study has measured the BOLD response as subjects attend to a block paradigm visual stimulus that forces activation to cross or not to cross the white matter region known as the corpus callosum. Two approaches to data analysis (parametric mapping and exploratory data analysis) have been employed and we have found a greater BOLD response during 'crossed' rather than 'uncrossed' stimulus in a region that includes the corpus callosum, with a confidence of p = 0.05. Further, it has been shown that exploratory data analysis detects this activity to a higher significance level and its results are consistent with known physiology.

ISBN: 0612941167Subjects--Topical Terms:

1017681
Biophysics, Medical.

Isolating bold fMRI correlates of interhemispheric visual processing: A comparison of parametric and exploratory analysis techniques.
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100 1 $a Hamilton, Andrew A. J. $3 1939525
245 1 0 $a Isolating bold fMRI correlates of interhemispheric visual processing: A comparison of parametric and exploratory analysis techniques.
300 $a 73 p.
500 $a Source: Masters Abstracts International, Volume: 43-02, page: 0501.
500 $a Adviser: Gerhard Stroink.
502 $a Thesis (M.Sc.)--Dalhousie University (Canada), 2004.
520 $a Blood-oxygen level-dependent (BOLD) functional MRI is currently used to measure the haemodynamic response in gray matter regions of the brain, but activity in these regions is thought to represent only the input signal to a neuron. It is also important to measure the output and the connectivity of neural activation (in white matter), but the BOLD contrast in this respect suffers from very low SNR and activation has proven difficult to detect. This study has measured the BOLD response as subjects attend to a block paradigm visual stimulus that forces activation to cross or not to cross the white matter region known as the corpus callosum. Two approaches to data analysis (parametric mapping and exploratory data analysis) have been employed and we have found a greater BOLD response during 'crossed' rather than 'uncrossed' stimulus in a region that includes the corpus callosum, with a confidence of p = 0.05. Further, it has been shown that exploratory data analysis detects this activity to a higher significance level and its results are consistent with known physiology.
590 $a School code: 0328.
650 4 $a Biophysics, Medical. $3 1017681
650 4 $a Health Sciences, Radiology. $3 1019076
690 $a 0760
690 $a 0574
710 2 0 $a Dalhousie University (Canada). $3 1017625
773 0 $t Masters Abstracts International $g 43-02.
790 1 0 $a Stroink, Gerhard, $e advisor
790 $a 0328
791 $a M.Sc.
792 $a 2004
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MQ94116