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Identification of novel cytotoxic ag...

Wynter, Sherine.

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Identification of novel cytotoxic agents from the dinoflagellate symbiont of the gorgonian Erythropodium caribaeorum.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Identification of novel cytotoxic agents from the dinoflagellate symbiont of the gorgonian Erythropodium caribaeorum./
Author:	Wynter, Sherine.
Description:	83 p.
Notes:	Source: Masters Abstracts International, Volume: 42-03, page: 1033.
Contained By:	Masters Abstracts International42-03.
Subject:	Engineering, Marine and Ocean. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1417203
ISBN:	0496219871

Identification of novel cytotoxic agents from the dinoflagellate symbiont of the gorgonian Erythropodium caribaeorum.
Wynter, Sherine.

Identification of novel cytotoxic agents from the dinoflagellate symbiont of the gorgonian Erythropodium caribaeorum. - 83 p.

Source: Masters Abstracts International, Volume: 42-03, page: 1033.

Thesis (M.S.)--Florida Atlantic University, 2004.

Erythropodium caribaeorum is an octocoral known for its production of novel anticancer agents, such as eleutherobin and its analogs as well as for its complex association with symbiotic dinoflagellates (Zooxanthellae; genus Symbiodimum).

ISBN: 0496219871Subjects--Topical Terms:

1019064
Engineering, Marine and Ocean.

Identification of novel cytotoxic agents from the dinoflagellate symbiont of the gorgonian Erythropodium caribaeorum.
LDR:01855nmm 2200301 4500 001 1849900
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008 130614s2004 eng d
020 $a 0496219871
035 $a (UnM)AAI1417203
035 $a AAI1417203
040 $a UnM $c UnM
100 1 $a Wynter, Sherine. $3 1937832
245 1 0 $a Identification of novel cytotoxic agents from the dinoflagellate symbiont of the gorgonian Erythropodium caribaeorum.
300 $a 83 p.
500 $a Source: Masters Abstracts International, Volume: 42-03, page: 1033.
500 $a Adviser: Russell G. Kerr.
502 $a Thesis (M.S.)--Florida Atlantic University, 2004.
520 $a Erythropodium caribaeorum is an octocoral known for its production of novel anticancer agents, such as eleutherobin and its analogs as well as for its complex association with symbiotic dinoflagellates (Zooxanthellae; genus Symbiodimum).
520 $a With this in mind, two sets of experiments were conducted using the extracts of the symbiotic algal cells from Erythropodium caribaeorum: an isolation and characterization of a novel tri-hydroxy sterol and a bioassay-guided isolation of three additional compounds. All compounds exhibit significant bioactivity against the following three cell lines: the human melanoma cell line M14P, the colon cancer cell line RKO and the breast cancer cell line MDA-MB-231. Importantly, this study reports the first isolation of a bioactive polyhydroxy sterol from a gorgonian's symbiont and further suggests that these algae represent a promising sustainable resource for drug discovery.
590 $a School code: 0119.
650 4 $a Engineering, Marine and Ocean. $3 1019064
650 4 $a Chemistry, Biochemistry. $3 1017722
650 4 $a Engineering, Biomedical. $3 1017684
690 $a 0547
690 $a 0487
690 $a 0541
710 2 0 $a Florida Atlantic University. $3 1017837
773 0 $t Masters Abstracts International $g 42-03.
790 1 0 $a Kerr, Russell G., $e advisor
790 $a 0119
791 $a M.S.
792 $a 2004
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1417203