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The fetal origins hypothesis and the...

Clarkin, Patrick Francis.

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The fetal origins hypothesis and the Hmong diaspora: Effects of warfare, early malnutrition, and later modernization on adult health.

Record Type:	Electronic resources : Monograph/item
Title/Author:	The fetal origins hypothesis and the Hmong diaspora: Effects of warfare, early malnutrition, and later modernization on adult health./
Author:	Clarkin, Patrick Francis.
Description:	311 p.
Notes:	Source: Dissertation Abstracts International, Volume: 65-08, Section: A, page: 3045.
Contained By:	Dissertation Abstracts International65-08A.
Subject:	Anthropology, Physical. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3142772
ISBN:	049600543X

The fetal origins hypothesis and the Hmong diaspora: Effects of warfare, early malnutrition, and later modernization on adult health.
Clarkin, Patrick Francis.

The fetal origins hypothesis and the Hmong diaspora: Effects of warfare, early malnutrition, and later modernization on adult health. - 311 p.

Source: Dissertation Abstracts International, Volume: 65-08, Section: A, page: 3045.

Thesis (Ph.D.)--State University of New York at Binghamton, 2004.

A fetus or infant exposed to malnutrition may reduce its rate of growth in order to adapt to inadequate resources. However, the fetal origins hypothesis predicts that such reductions in growth may leave various organ systems functionally compromised, increasing the risk for obesity, type 2 diabetes, and cardiovascular disease later in life. Simultaneously, these conditions have long been associated with modernization. This dissertation explored how early malnutrition and later modernization affected chronic disease markers in Hmong refugees in French Guiana and the United States.

ISBN: 049600543XSubjects--Topical Terms:

877524
Anthropology, Physical.

The fetal origins hypothesis and the Hmong diaspora: Effects of warfare, early malnutrition, and later modernization on adult health.
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100 1 $a Clarkin, Patrick Francis. $3 1931723
245 1 4 $a The fetal origins hypothesis and the Hmong diaspora: Effects of warfare, early malnutrition, and later modernization on adult health.
300 $a 311 p.
500 $a Source: Dissertation Abstracts International, Volume: 65-08, Section: A, page: 3045.
500 $a Adviser: Michael A. Little.
502 $a Thesis (Ph.D.)--State University of New York at Binghamton, 2004.
520 $a A fetus or infant exposed to malnutrition may reduce its rate of growth in order to adapt to inadequate resources. However, the fetal origins hypothesis predicts that such reductions in growth may leave various organ systems functionally compromised, increasing the risk for obesity, type 2 diabetes, and cardiovascular disease later in life. Simultaneously, these conditions have long been associated with modernization. This dissertation explored how early malnutrition and later modernization affected chronic disease markers in Hmong refugees in French Guiana and the United States.
520 $a The Hmong diaspora has its origins in Laos, where the Second Indochina War (1958--1975) disrupted food production practices for much of the rural population. This study included 288 Hmong males and females (180 in French Guiana, 108 in the United States) aged 18--51 years who were born during the war. Individuals born in high-conflict areas were presumed to have experienced prenatal malnutrition, while those who were displaced from their village before age 2 years were presumed to have experienced malnutrition in infancy. Individuals who resided in the United States were considered to have more exposure to modernization compared to those in French Guiana.
520 $a In a stepwise regression analysis, Hmong who resided in the U.S. had a significantly higher central skinfold ratio and lower arm muscle area, while age at first resettlement was positively associated with higher blood pressure and shorter stature. Individuals born in a war zone had a significantly higher body mass index, abdominal/hip ratio, and a central skinfold ratio than those born in a safe zone. Also, Hmong who were displaced from their village before age 2 years had higher blood pressure and shorter stature than those who were not. It appears that early malnutrition resulting from conditions of war has had detrimental effects on growth and development after controlling for degree of modernization in adulthood. Finally, Hmong in the United States had a higher adjusted odds ratio for pre-hypertension in a logistic regression analysis, indicating that modernization is also a factor in chronic disease development.
590 $a School code: 0792.
650 4 $a Anthropology, Physical. $3 877524
650 4 $a Health Sciences, Nutrition. $3 1017801
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690 $a 0570
710 2 0 $a State University of New York at Binghamton. $3 737493
773 0 $t Dissertation Abstracts International $g 65-08A.
790 1 0 $a Little, Michael A., $e advisor
790 $a 0792
791 $a Ph.D.
792 $a 2004
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3142772