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Exercise-induced bronchoconstriction...

Evans, Tina Marie.

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Exercise-induced bronchoconstriction during room temperature and cold temperature exercise and eucapnic voluntary hyperventilation.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Exercise-induced bronchoconstriction during room temperature and cold temperature exercise and eucapnic voluntary hyperventilation./
Author:	Evans, Tina Marie.
Description:	165 p.
Notes:	Source: Dissertation Abstracts International, Volume: 66-05, Section: B, page: 2506.
Contained By:	Dissertation Abstracts International66-05B.
Subject:	Health Sciences, Medicine and Surgery. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3176915
ISBN:	0542160919

Exercise-induced bronchoconstriction during room temperature and cold temperature exercise and eucapnic voluntary hyperventilation.
Evans, Tina Marie.

Exercise-induced bronchoconstriction during room temperature and cold temperature exercise and eucapnic voluntary hyperventilation. - 165 p.

Source: Dissertation Abstracts International, Volume: 66-05, Section: B, page: 2506.

Thesis (Ph.D.)--Marywood University, 2005.

Introduction. Exercise-induced bronchoconstriction (EIB) is thought to result from osmotic and thermal events of air conditioning exercise at high ventilation rates. The purpose of this study was to evaluate lung function after exercise and eucapnic voluntary hyperventilation (EVH) while breathing both room temperature and cold temperature dry bottled air. Methods. Twenty-two subjects were identified as EIB probable by a fall of ≥7% in forced expiratory volume in the first one second of exhalation (FEV1) using a six-minute room temperature (22.0°C) EVH challenge (RTEVH). Subjects then randomly performed three six minute challenges: cold temperature EVH (CTEVH; -1°C), room temperature exercise (RTEX; 22.0°C) and cold temperature exercise (CTEX; -1°C), with a period of at least 48 hours observed between challenges. Spirometry and impulse oscillometry were performed at baseline and at 5, 10, 15 and 20 minutes post-challenge. Results. Reasonable agreement was found between challenge modes and room temperature and cold temperature challenges. RTEVH resulted in a significantly greater peak fall in FEV1 than CTEX (p = .048); no other differences in FEV1 were observed. Conclusion. Strong correlations were observed within testing modalities for post-EVH and post-exercise testing values. Spirometry revealed little difference between challenges, however, impulse oscillometry detected differences in the degree of response, with RTEVH and RTEX being identified as the more potent challenges. Similar post-challenge falls in FEV1 for room and cold temperature EVH and exercise suggest that dryness is essential to test conditions, as cold temperature did not have an additive effect to the EIB response. The potential role of impulse oscillometry in the evaluation of EIB is deserving of further study.

ISBN: 0542160919Subjects--Topical Terms:

1017756
Health Sciences, Medicine and Surgery.

Exercise-induced bronchoconstriction during room temperature and cold temperature exercise and eucapnic voluntary hyperventilation.
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100 1 $a Evans, Tina Marie. $3 1906408
245 1 0 $a Exercise-induced bronchoconstriction during room temperature and cold temperature exercise and eucapnic voluntary hyperventilation.
300 $a 165 p.
500 $a Source: Dissertation Abstracts International, Volume: 66-05, Section: B, page: 2506.
500 $a Chair: Alan Levine.
502 $a Thesis (Ph.D.)--Marywood University, 2005.
520 $a Introduction. Exercise-induced bronchoconstriction (EIB) is thought to result from osmotic and thermal events of air conditioning exercise at high ventilation rates. The purpose of this study was to evaluate lung function after exercise and eucapnic voluntary hyperventilation (EVH) while breathing both room temperature and cold temperature dry bottled air. Methods. Twenty-two subjects were identified as EIB probable by a fall of ≥7% in forced expiratory volume in the first one second of exhalation (FEV1) using a six-minute room temperature (22.0°C) EVH challenge (RTEVH). Subjects then randomly performed three six minute challenges: cold temperature EVH (CTEVH; -1°C), room temperature exercise (RTEX; 22.0°C) and cold temperature exercise (CTEX; -1°C), with a period of at least 48 hours observed between challenges. Spirometry and impulse oscillometry were performed at baseline and at 5, 10, 15 and 20 minutes post-challenge. Results. Reasonable agreement was found between challenge modes and room temperature and cold temperature challenges. RTEVH resulted in a significantly greater peak fall in FEV1 than CTEX (p = .048); no other differences in FEV1 were observed. Conclusion. Strong correlations were observed within testing modalities for post-EVH and post-exercise testing values. Spirometry revealed little difference between challenges, however, impulse oscillometry detected differences in the degree of response, with RTEVH and RTEX being identified as the more potent challenges. Similar post-challenge falls in FEV1 for room and cold temperature EVH and exercise suggest that dryness is essential to test conditions, as cold temperature did not have an additive effect to the EIB response. The potential role of impulse oscillometry in the evaluation of EIB is deserving of further study.
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