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Cardiac repair using fibrin patch-ba...

Xiong, Qiang.

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Cardiac repair using fibrin patch-based enhanced delivery of stem cells and novel strategies for fast examination of myocaridal energetics in vivo using 31P magnetic resonance spectroscopy.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Cardiac repair using fibrin patch-based enhanced delivery of stem cells and novel strategies for fast examination of myocaridal energetics in vivo using 31P magnetic resonance spectroscopy./
作者:	Xiong, Qiang.
面頁冊數:	164 p.
附註:	Source: Dissertation Abstracts International, Volume: 72-06, Section: B, page: .
Contained By:	Dissertation Abstracts International72-06B.
標題:	Engineering, Biomedical. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3449171
ISBN:	9781124556857

Cardiac repair using fibrin patch-based enhanced delivery of stem cells and novel strategies for fast examination of myocaridal energetics in vivo using 31P magnetic resonance spectroscopy.
Xiong, Qiang.

Cardiac repair using fibrin patch-based enhanced delivery of stem cells and novel strategies for fast examination of myocaridal energetics in vivo using 31P magnetic resonance spectroscopy. - 164 p.

Source: Dissertation Abstracts International, Volume: 72-06, Section: B, page: .

Thesis (Ph.D.)--University of Minnesota, 2011.

The dissertation is related to heart disease in both basic scientific and pre-clinic respects.

ISBN: 9781124556857Subjects--Topical Terms:

1017684
Engineering, Biomedical.

Cardiac repair using fibrin patch-based enhanced delivery of stem cells and novel strategies for fast examination of myocaridal energetics in vivo using 31P magnetic resonance spectroscopy.
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245 1 0 $a Cardiac repair using fibrin patch-based enhanced delivery of stem cells and novel strategies for fast examination of myocaridal energetics in vivo using 31P magnetic resonance spectroscopy.
300 $a 164 p.
500 $a Source: Dissertation Abstracts International, Volume: 72-06, Section: B, page: .
500 $a Adviser: Jianyi Zhang.
502 $a Thesis (Ph.D.)--University of Minnesota, 2011.
520 $a The dissertation is related to heart disease in both basic scientific and pre-clinic respects.
520 $a Cardiovascular disease is a leading cause of death in the developed countries even with optimal medical treatment. Recently, the emerging stem cell biology has shown great potentials for cardiac repair. Using both large (swine) and small (rodent) animal models with ischemic heart disease, we examined the functional improvement of enhanced delivery of combined human embryonic stem cell-derived endothelial cells and smooth muscle cells via a fibrin 3D porous scaffold biomatrix. The integration of stem cell biology and tissue engineering has resulted in significant improvement of both regional and global left ventricle function as compared to untreated animals, demonstrating a promising therapeutic strategy of using this cell type and the novel mode of delivery.
520 $a As a most energy demanding organ, the heart energetic status is tightly associated with the organ's physiological and pathological conditions. Based on the ultra-high-field magnetic resonance imaging/spectroscopy techniques, we developed a noninvasive modality for rapid examination of cardiac energetics in vivo. The new platform will offer unprecedented understanding into the relationship between the cardiac energetic status and the organ's physiological/pathological conditions, and thus it is of great potential in both basic scientific research and clinical diagnosis.
590 $a School code: 0130.
650 4 $a Engineering, Biomedical. $3 1017684
650 4 $a Health Sciences, Radiology. $3 1019076
690 $a 0541
690 $a 0574
710 2 $a University of Minnesota. $b Biomedical Engineering. $3 1669049
773 0 $t Dissertation Abstracts International $g 72-06B.
790 1 0 $a Zhang, Jianyi, $e advisor
790 1 0 $a Vaughan, J. Thomas $e committee member
790 1 0 $a Chen, Wei $e committee member
790 1 0 $a Wang, Chun $e committee member
790 1 0 $a Taton, T. Adrew $e committee member
790 $a 0130
791 $a Ph.D.
792 $a 2011
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3449171