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Dose-Response Models of Rickettsiae ...

Tamrakar, Sushil Bahadur.

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Dose-Response Models of Rickettsiae and Other Biological Agents of Concern.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Dose-Response Models of Rickettsiae and Other Biological Agents of Concern./
Author:	Tamrakar, Sushil Bahadur.
Description:	219 p.
Notes:	Source: Dissertation Abstracts International, Volume: 72-06, Section: B, page: .
Contained By:	Dissertation Abstracts International72-06B.
Subject:	Biology, Microbiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3452481
ISBN:	9781124593319

Dose-Response Models of Rickettsiae and Other Biological Agents of Concern.
Tamrakar, Sushil Bahadur.

Dose-Response Models of Rickettsiae and Other Biological Agents of Concern. - 219 p.

Source: Dissertation Abstracts International, Volume: 72-06, Section: B, page: .

Thesis (Ph.D.)--Drexel University, 2011.

A dose-response relationship describes the relationship between the level of microbial exposure (doses) and likelihood of occurrence of an adverse health effects. It is a key ingredient of microbial risk assessment paradigm. Dose-response modeling now appears to be widely used for food and water microbial risk assessments. The thesis focuses on development of dose-response models of Rickettsiae and some other pathogens listed as bioterrorism agents by CDC.

ISBN: 9781124593319Subjects--Topical Terms:

1017734
Biology, Microbiology.

Dose-Response Models of Rickettsiae and Other Biological Agents of Concern.
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020 $a 9781124593319
035 $a (UMI)AAI3452481
035 $a AAI3452481
040 $a UMI $c UMI
100 1 $a Tamrakar, Sushil Bahadur. $3 1679956
245 1 0 $a Dose-Response Models of Rickettsiae and Other Biological Agents of Concern.
300 $a 219 p.
500 $a Source: Dissertation Abstracts International, Volume: 72-06, Section: B, page: .
500 $a Adviser: Charles N. Haas.
502 $a Thesis (Ph.D.)--Drexel University, 2011.
520 $a A dose-response relationship describes the relationship between the level of microbial exposure (doses) and likelihood of occurrence of an adverse health effects. It is a key ingredient of microbial risk assessment paradigm. Dose-response modeling now appears to be widely used for food and water microbial risk assessments. The thesis focuses on development of dose-response models of Rickettsiae and some other pathogens listed as bioterrorism agents by CDC.
520 $a Rickettsial diseases are a group of infections to humans caused by rickettsiae. The rickettsiae are small, Gram-negative, aerobic, coccobacillary bacteria that are obligate intracellular parasites of eucaryotic cells with a life cycle involving both vertebrate and invertebrate hosts. Among several rickettsial diseases, Rocky Mountain spotted fever caused by R. rickettsii and endemic typhus caused by R. typhi are diseases of concern in the thesis. Besides classical dose-response models of rickettsial diseases, development of multi-routes dose-response models, interspecies susceptibilities and outbreak analysis of rickettsial diseases have been analyzed and presented in the study.
520 $a Moreover, the study also includes dose-response models of Coxiella burnetii (Q fever), Burkholderia pseudomallei (Melioidosis) and Lassa virus fever. The development and analysis of dose-response models will help to the concern authorities and decision makers to cope emergency situation and formulating guidelines such as minimum detection limits, evacuation volume etc.
590 $a School code: 0065.
650 4 $a Biology, Microbiology. $3 1017734
650 4 $a Environmental Health. $3 578282
650 4 $a Engineering, Environmental. $3 783782
690 $a 0410
690 $a 0470
690 $a 0775
710 2 $a Drexel University. $3 1018434
773 0 $t Dissertation Abstracts International $g 72-06B.
790 1 0 $a Haas, Charles N., $e advisor
790 $a 0065
791 $a Ph.D.
792 $a 2011
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3452481