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Nanoscale approaches for biomolecule...

Goyal, Swati.

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Nanoscale approaches for biomolecule separation and detection.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Nanoscale approaches for biomolecule separation and detection./
Author:	Goyal, Swati.
Description:	71 p.
Notes:	Source: Masters Abstracts International, Volume: 48-04, page: 2475.
Contained By:	Masters Abstracts International48-04.
Subject:	Biology, Molecular. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1474206
ISBN:	9781109627923

Nanoscale approaches for biomolecule separation and detection.
Goyal, Swati.

Nanoscale approaches for biomolecule separation and detection. - 71 p.

Source: Masters Abstracts International, Volume: 48-04, page: 2475.

Thesis (M.S.)--The University of Texas at Arlington, 2009.

Nanotechnology has the potential to contact and impact the biological interactions at the most basic chemical and physical levels. New approaches to nanodevices allow high sensitivity and specificity with low sample requirement. Such devices are potential candidates for early disease detection at molecular levels and have important implications in associated therapeutics.

ISBN: 9781109627923Subjects--Topical Terms:

1017719
Biology, Molecular.

Nanoscale approaches for biomolecule separation and detection.
LDR:02309nam 2200325 4500 001 1400274
005 20111005095643.5
008 130515s2009 ||||||||||||||||| ||eng d
020 $a 9781109627923
035 $a (UMI)AAI1474206
035 $a AAI1474206
040 $a UMI $c UMI
100 1 $a Goyal, Swati. $3 1679310
245 1 0 $a Nanoscale approaches for biomolecule separation and detection.
300 $a 71 p.
500 $a Source: Masters Abstracts International, Volume: 48-04, page: 2475.
500 $a Adviser: Samir M. Iqbal.
502 $a Thesis (M.S.)--The University of Texas at Arlington, 2009.
520 $a Nanotechnology has the potential to contact and impact the biological interactions at the most basic chemical and physical levels. New approaches to nanodevices allow high sensitivity and specificity with low sample requirement. Such devices are potential candidates for early disease detection at molecular levels and have important implications in associated therapeutics.
520 $a This research work focuses on two different areas: developing devices for DNA detection, protein enrichment and exploring material properties to fabricate microscale/nanoscale structures. In one approach, hairpin probe DNA was used to detect fmol of ss-DNA from k-ras oncogene. In another approach, nanochannel based device was developed to selectively increase the concentration of one protein from a mixture of proteins taking advantage of antigen-antibody interactions in nanochannels. The phenomenon was demonstrated with selective separation of BSA and human hemoglobin. Further, effect of fluorescence on fluid flow through channels was studied.
520 $a Towards biocompatible membranes, a rapid, simple and inexpensive approach to fabricate microchannels from 100-700 micron was developed. These channels were made in PDMS using simple chemistry and materials like nanoparticles, polyurethane and acetone, at various curing temperatures.
590 $a School code: 2502.
650 4 $a Biology, Molecular. $3 1017719
650 4 $a Nanoscience. $3 587832
690 $a 0307
690 $a 0565
710 2 $a The University of Texas at Arlington. $b Biomedical Engineering. $3 1264771
773 0 $t Masters Abstracts International $g 48-04.
790 1 0 $a Iqbal, Samir M., $e advisor
790 1 0 $a Kim, Young-Tae $e committee member
790 1 0 $a Romero-Ortega, Mario I. $e committee member
790 $a 2502
791 $a M.S.
792 $a 2009
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1474206