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Uniform dielectric barrier discharge...

Ayan, Halim.

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Uniform dielectric barrier discharge with nanosecond pulse excitation for biomedical applications.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Uniform dielectric barrier discharge with nanosecond pulse excitation for biomedical applications./
作者:	Ayan, Halim.
面頁冊數:	90 p.
附註:	Source: Dissertation Abstracts International, Volume: 70-07, Section: B, page: 4260.
Contained By:	Dissertation Abstracts International70-07B.
標題:	Engineering, Biomedical. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3367935
ISBN:	9781109284775

Uniform dielectric barrier discharge with nanosecond pulse excitation for biomedical applications.
Ayan, Halim.

Uniform dielectric barrier discharge with nanosecond pulse excitation for biomedical applications. - 90 p.

Source: Dissertation Abstracts International, Volume: 70-07, Section: B, page: 4260.

Thesis (Ph.D.)--Drexel University, 2009.

For some period of time the use of plasma in medicine has been limited to thermal discharges for cauterization and dissection. The effects of thermal plasma on tissue are entirely related to local heating. Non-thermal plasma, on the other hand, can have many different modes of interaction with tissue. It has been recently demonstrated that direct treatment of smooth surfaces by non-thermal dielectric barrier discharge (DBD) in air is highly effective in killing pathogens. Moreover, DBD can create different sub-lethal and selective effects. These results hold significant promise for medical applications such as sterilization of wound surfaces. However, a typical DBD in air can be highly non-uniform, particularly on topographically non-uniform surfaces such as in most living tissues. This creates significant limitations for use of DBDs in wound care and other biomedical applications. In this thesis, a novel non-thermal plasma system, namely nanosecond-pulsed DBD, has been developed and investigated to address this important limitation. Nanosecond-pulsed DBD is shown to be uniform in air at atmospheric pressure and much more effective in killing bacteria than conventional DBDs, particularly on topographically non-uniform surfaces. Thus, this new plasma system is potentially convenient for in vivo and hospital sterilization cases.

ISBN: 9781109284775Subjects--Topical Terms:

1017684
Engineering, Biomedical.

Uniform dielectric barrier discharge with nanosecond pulse excitation for biomedical applications.
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500 $a Source: Dissertation Abstracts International, Volume: 70-07, Section: B, page: 4260.
500 $a Advisers: Gary Friedman; Alexander Fridman.
502 $a Thesis (Ph.D.)--Drexel University, 2009.
520 $a For some period of time the use of plasma in medicine has been limited to thermal discharges for cauterization and dissection. The effects of thermal plasma on tissue are entirely related to local heating. Non-thermal plasma, on the other hand, can have many different modes of interaction with tissue. It has been recently demonstrated that direct treatment of smooth surfaces by non-thermal dielectric barrier discharge (DBD) in air is highly effective in killing pathogens. Moreover, DBD can create different sub-lethal and selective effects. These results hold significant promise for medical applications such as sterilization of wound surfaces. However, a typical DBD in air can be highly non-uniform, particularly on topographically non-uniform surfaces such as in most living tissues. This creates significant limitations for use of DBDs in wound care and other biomedical applications. In this thesis, a novel non-thermal plasma system, namely nanosecond-pulsed DBD, has been developed and investigated to address this important limitation. Nanosecond-pulsed DBD is shown to be uniform in air at atmospheric pressure and much more effective in killing bacteria than conventional DBDs, particularly on topographically non-uniform surfaces. Thus, this new plasma system is potentially convenient for in vivo and hospital sterilization cases.
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