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Bioisosteres in medicinal chemistry

Brown, Nathan.

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Bioisosteres in medicinal chemistry

Record Type:	Electronic resources : Monograph/item
Title/Author:	Bioisosteres in medicinal chemistry/ edited by Nathan Brown.
other author:	Brown, Nathan.
Published:	Hoboken :John Wiley & Sons, : 2012.,
Description:	1 online resource.
Subject:	Drugs - Design. -
Online resource:	http://onlinelibrary.wiley.com/book/10.1002/9783527654307
ISBN:	9783527654307 (electronic bk.)

Bioisosteres in medicinal chemistry
Bioisosteres in medicinal chemistry[electronic resource] /edited by Nathan Brown. - Hoboken :John Wiley & Sons,2012. - 1 online resource. - Methods and principles in medicinal chemistry ;v. 54. - Methods and principles in medicinal chemistry ;v. 39..

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologi.

ISBN: 9783527654307 (electronic bk.)Subjects--Topical Terms:

664528
Drugs
--Design.

LC Class. No.: RS420

Dewey Class. No.: 615.19

Bioisosteres in medicinal chemistry
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020 $a 9783527654307 (electronic bk.)
020 $a 3527654305 (electronic bk.)
020 $a 9783527654338 (electronic bk.)
020 $a 352765433X (electronic bk.)
020 $a 9781280778537 (MyiLibrary)
020 $a 1280778539 (MyiLibrary)
020 $z 9783527330157
035 $a (OCoLC)809920141 $z (OCoLC)796383251 $z (OCoLC)796932644
035 $a ocn809920141
040 $a DG1 $b eng $c DG1 $d OCLCO $d OCLCQ $d EBLCP $d N $d IDEBK $d CUS $d OCLCQ $d SFB $d OCLCQ $d YDXCP $d COO $d OHI $d OCLCF $d OCLCA $d OCLCQ
050 4 $a RS420
082 0 4 $a 615.19 $2 22
245 0 0 $a Bioisosteres in medicinal chemistry $h [electronic resource] / $c edited by Nathan Brown.
260 $a Hoboken : $b John Wiley & Sons, $c 2012.
300 $a 1 online resource.
490 1 $a Methods and principles in medicinal chemistry ; $v v. 54
520 $a Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologi.
588 0 $a Print version record.
650 0 $a Drugs $x Design. $3 664528
650 0 $a Pharmaceutical chemistry. $3 550956
700 1 $a Brown, Nathan. $3 2148923
710 2 $a Wiley InterScience (Online service) $3 1597786
830 0 $a Methods and principles in medicinal chemistry ; $v v. 39. $3 1965686
856 4 0 $u http://onlinelibrary.wiley.com/book/10.1002/9783527654307