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Drug stereochemistry = analytical me...

Jozwiak, Krzysztof, (1971-)

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Drug stereochemistry = analytical methods and pharmacology /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Drug stereochemistry/ edited by Krzysztof J�o�zwiak, W. John Lough, Irving W. Wainer.
Reminder of title:	analytical methods and pharmacology /
other author:	Jozwiak, Krzysztof,
Published:	New York :Informa Healthcare, : 2012.,
Description:	x, 322 p. :ill.
[NT 15003449]:	pt. 1. Introduction -- pt. 2. The separation, preparation, and identification of stereochemically pure drugs -- pt. 3. Pharmacokinetic and pharmacodynamic differences between drug stereoisomers -- pt. 4. Perspectives on the development and use of single isomer drugs.
Subject:	Pharmaceutical chemistry. -
Online resource:	http://marc.crcnetbase.com/isbn/9781420092394Distributed by publisher. Purchase or institutional license may be required for access.
ISBN:	9781420092394 (ebook : PDF)

Drug stereochemistry = analytical methods and pharmacology /
Drug stereochemistryanalytical methods and pharmacology /[electronic resource] :edited by Krzysztof J�o�zwiak, W. John Lough, Irving W. Wainer. - 3rd ed. - New York :Informa Healthcare,2012. - x, 322 p. :ill. - Drugs and the pharmaceutical science series ;211. - Drugs and the pharmaceutical sciences ;v. 183-184.

Includes bibliographical references and index.

pt. 1. Introduction -- pt. 2. The separation, preparation, and identification of stereochemically pure drugs -- pt. 3. Pharmacokinetic and pharmacodynamic differences between drug stereoisomers -- pt. 4. Perspectives on the development and use of single isomer drugs.

"Updated to reflect modern advances in the techniques and methodology of drug stereochemistry, the Third Edition comprehensively presents all aspects of chiral drugs from scientific, academic, governmental, industrial, and clinical points of view. This stand-alone text covers the lifespan of stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs. New topics in the Third Edition include: The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery; How stereochemistry impacts decisions made in the Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) stages of drug discovery; A chapter on pharmacokinetics and pharmacodynamics that discusses the issues faced during the final stages of the drug development process; The impact of International Conference on Harmonisation on the use of single isomer drugs; Racemic switches; The concept of molecular chiral recognition and how it affects the separation and behavior of stereochemically pure drugs; A chapter on the legal perspectives of patent issues surrounding racemic switches and the marketing of single enantiomer switches"--Provided by publisher.

Mode of access: World Wide Web.

ISBN: 9781420092394 (ebook : PDF)Subjects--Topical Terms:

550956
Pharmaceutical chemistry.
Index Terms--Genre/Form:

542853
Electronic books.

Drug stereochemistry = analytical methods and pharmacology /
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092 $a 615.19 $b D794
245 0 0 $a Drug stereochemistry $h [electronic resource] : $b analytical methods and pharmacology / $c edited by Krzysztof J�o�zwiak, W. John Lough, Irving W. Wainer.
250 $a 3rd ed.
260 $a New York : $b Informa Healthcare, $c 2012.
300 $a x, 322 p. : $b ill.
490 1 $a Drugs and the pharmaceutical science series ; $v 211
504 $a Includes bibliographical references and index.
505 0 $a pt. 1. Introduction -- pt. 2. The separation, preparation, and identification of stereochemically pure drugs -- pt. 3. Pharmacokinetic and pharmacodynamic differences between drug stereoisomers -- pt. 4. Perspectives on the development and use of single isomer drugs.
520 $a "Updated to reflect modern advances in the techniques and methodology of drug stereochemistry, the Third Edition comprehensively presents all aspects of chiral drugs from scientific, academic, governmental, industrial, and clinical points of view. This stand-alone text covers the lifespan of stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs. New topics in the Third Edition include: The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery; How stereochemistry impacts decisions made in the Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) stages of drug discovery; A chapter on pharmacokinetics and pharmacodynamics that discusses the issues faced during the final stages of the drug development process; The impact of International Conference on Harmonisation on the use of single isomer drugs; Racemic switches; The concept of molecular chiral recognition and how it affects the separation and behavior of stereochemically pure drugs; A chapter on the legal perspectives of patent issues surrounding racemic switches and the marketing of single enantiomer switches"--Provided by publisher.
530 $a Also available in print edition.
538 $a Mode of access: World Wide Web.
650 0 $a Pharmaceutical chemistry. $3 550956
650 0 $a Stereochemistry. $3 673465
650 0 $a Chiral drugs. $3 686368
655 7 $a Electronic books. $2 lcsh $3 542853
700 1 $a Jozwiak, Krzysztof, $d 1971- $3 1603258
700 1 $a Lough, W. J. $q (W. John) $3 1603259
700 1 $a Wainer, Irving W. $3 680927
776 1 $z 9781420092387 (hardback : alk. paper) $z 1420092383
830 0 $a Drugs and the pharmaceutical sciences ; $v v. 183-184 $3 1359366
856 4 0 $u http://marc.crcnetbase.com/isbn/9781420092394 $q application/PDF $z Distributed by publisher. Purchase or institutional license may be required for access.