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Ichthyoses = clinical, biochemical, ...

Elias, Peter M.

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Ichthyoses = clinical, biochemical, pathogenic and diagnostic assessment /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Ichthyoses/ Peter M. Elias ... [et al.].
Reminder of title:	clinical, biochemical, pathogenic and diagnostic assessment /
other author:	Elias, Peter M.
Published:	Basel [Switzerland] ;Karger, : c2010.,
Description:	1 online resource (ix, 144 p.) :ill. (some col.)
Subject:	Ichthyosis. -
Online resource:	http://content.karger.com/produkteDB/produkte.asp?Aktion=ShowEachType&ProduktNr=254153
ISBN:	9783805593953 (electronic bk.)

Ichthyoses = clinical, biochemical, pathogenic and diagnostic assessment /
Ichthyosesclinical, biochemical, pathogenic and diagnostic assessment /[electronic resource] :Peter M. Elias ... [et al.]. - Basel [Switzerland] ;Karger,c2010. - 1 online resource (ix, 144 p.) :ill. (some col.) - Current problems in dermatology,v. 391421-5721 ;. - Current problems in dermatology ;v. 37..

Includes bibliographical references and index.

The various manifestations of ichthyoses are classified either by their appearance or their molecular genetics. This volume focuses on generalized, inherited disorders of cornification, which constitute an ever-enlarging group of monogenic diseases caused by a large number of genes that affect a broad array of cellular functions. The authors' overview reflects their unique perspective that the clinical phenotype in the inherited ichthyoses mirrors a 'best attempt' by a metabolically compromised epidermis to maintain a barrier sufficiently impermeable for survival in a desiccating external environment. The basis for threats to survival is illuminated, and the systemic problems, including growth failure, also reflect a compromised barrier. A new consensus classification of these disorders is provided, and the distinguishing clinical features of each disorder are described. Further, the latest molecular genetic information is succinctly reviewed with up-to-date and comprehensive references. Yet, the major emphases of this volume are on disease pathogenesis and on the identification of key ultrastructural features. This publication will prove an invaluable aid to dermatologists, pediatric dermatologists and pediatricians dealing with patients with inherited ichthyoses. In addition, clinical geneticists and dermatopathologists will find it interesting reading.

ISBN: 9783805593953 (electronic bk.)Subjects--Topical Terms:

1602711
Ichthyosis.
Index Terms--Genre/Form:

542853
Electronic books.

LC Class. No.: RL435 / .I18 2010

Dewey Class. No.: 616.5/44

National Library of Medicine Call No.: W1 / CU804L v.39 2010

Ichthyoses = clinical, biochemical, pathogenic and diagnostic assessment /
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020 $a 3805593953 (electronic bk.)
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245 0 0 $a Ichthyoses $h [electronic resource] : $b clinical, biochemical, pathogenic and diagnostic assessment / $c Peter M. Elias ... [et al.].
260 $a Basel [Switzerland] ; $a New York : $b Karger, $c c2010.
300 $a 1 online resource (ix, 144 p.) : $b ill. (some col.)
490 1 $a Current problems in dermatology, $x 1421-5721 ; $v v. 39
504 $a Includes bibliographical references and index.
520 $a The various manifestations of ichthyoses are classified either by their appearance or their molecular genetics. This volume focuses on generalized, inherited disorders of cornification, which constitute an ever-enlarging group of monogenic diseases caused by a large number of genes that affect a broad array of cellular functions. The authors' overview reflects their unique perspective that the clinical phenotype in the inherited ichthyoses mirrors a 'best attempt' by a metabolically compromised epidermis to maintain a barrier sufficiently impermeable for survival in a desiccating external environment. The basis for threats to survival is illuminated, and the systemic problems, including growth failure, also reflect a compromised barrier. A new consensus classification of these disorders is provided, and the distinguishing clinical features of each disorder are described. Further, the latest molecular genetic information is succinctly reviewed with up-to-date and comprehensive references. Yet, the major emphases of this volume are on disease pathogenesis and on the identification of key ultrastructural features. This publication will prove an invaluable aid to dermatologists, pediatric dermatologists and pediatricians dealing with patients with inherited ichthyoses. In addition, clinical geneticists and dermatopathologists will find it interesting reading.
588 $a Description based on print version record.
650 0 $a Ichthyosis. $3 1602711
650 1 2 $a Ichthyosis $x diagnosis. $3 1602712
650 2 2 $a Ichthyosis $x genetics. $3 1602713
650 2 2 $a Ichthyosis $x pathology. $3 1602714
650 2 2 $a Skin Diseases $x diagnosis. $3 1602715
650 2 2 $a Skin Diseases $x genetics. $3 1602716
650 2 2 $a Skin Diseases $x pathology. $3 873358
655 4 $a Electronic books. $2 lcsh $3 542853
700 1 $a Elias, Peter M. $3 1602710
830 0 $a Current problems in dermatology ; $v v. 37. $3 1360650
856 4 0 $u http://content.karger.com/produkteDB/produkte.asp?Aktion=ShowEachType&ProduktNr=254153